One hundred and thirteen died from isolated pulmonary hypertension … Years ago, only the worst cases of systemic sclerosis (scleroderma) were diagnosed, thus leading to the widespread belief that systemic scleroderma was always progressive and fatal.. Now that the full range of types and severity of scleroderma are being recognized and diagnosed, there is increasing awareness that many people have a milder type of illness with a … It is characterized by scar tissue (fibrosis) on the skin and other organs. Fibrosis is caused by the production of too much collagen in the body. Diagnosis of scleroderma may be very difficult, particularly in its early stages. Only a few people get scleroderma, but no one really knows why. Many of its symptoms are common to, or may overlap with, those of other diseases, especially other autoimmune connective-tissue diseases such as rheumatoid arthritis and lupus. J Rheumatol. Although it most often affects the skin, scleroderma also can affect many other parts of the body. Barnett AJ, Miller MH, Littlejohn GO. Pictures of Systemic Sclerosis (Scleroderma) Symptoms of Systemic Sclerosis. A survival study of patients with scleroderma diagnosed over 30 years (1953-1983): the value of a simple cutaneous classification in the early stages of the disease. Fewer than 500,000 people in the United States have scleroderma. Pictures of Alopecia Scleroderma is a very rare cause of balding or hair thinning. Of the 2000 patients in the Pittsburgh scleroderma databank, 211 patients have died of lung disease over the past 20 years. Different symptoms may develop in stages over a very long In the earliest stages of scleroderma, the skin appears mildly inflamed with swelling and often redness. Recognition of the two types of lung disease is important because their predictors and treatment differ Pulmonary disease is now the leading cause of death in patients with scleroderma. The skin changes associated with limited scleroderma typically occur only in the lower arms and legs, below the elbows and knees, and sometimes affect the face and neck. 1988 Feb. 15(2):276-83. . Alopecia (hair loss) may occur with scleroderma… This video slideshow features images of scleroderma (systemic sclerosis) symptoms such as calcinosis, digital ulcers, gangrene, and Raynaud's. Scleroderma is a chronic and rare type of autoimmune disease that primarily targets the skin and the body’s connective tissues. Scleroderma is a chronic but rare autoimmune disease in which normal tissue is replaced with thick tissue with extra collagen. Overview. Systemic scleroderma is an autoimmune disease that affects the skin and internal organs. Overview. (Also see What is Scleroderma?, Types of Scleroderma, Scleroderma Symptoms, and Scleroderma Videos). Some experts report that six out of seven patients are women. SS may only affect the skin in the early stages of the disease. Limited scleroderma, also known as CREST syndrome, is one subtype of scleroderma — a condition whose name means "hardened skin." The disease involves progressive affectation of the body through gradual hardening and tightening of the skin and connective tissues – components of the body that are naturally meant to be elastic and flexible. Scleroderma is a long-lasting disease that affects your skin, connective tissue, and internal organs.It happens when your immune system causes … No one knows for sure why or how it develops. Scleroderma is a rare disease. Some people have a type of scleroderma called CREST syndrome (or limited scleroderma). The most common age span for scleroderma to develop is between 35 and 50. Collagen normally strengthens and supports connective tissues. The skin gradually thickens (more rapidly in the diffuse form) and the patient feels progressive “tightening” of the skin with decreased flexibility.

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